Prime IV Hydration & Wellness Franchises for Sale | VFR
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Health Care & Medical · Medical Spas & Aesthetics

Prime IV Hydration & Wellness Franchises for Sale

A retail IV hydration and wellness center offering nutrient IV drips, hormone and peptide therapy. Spa-style storefront, but a licensed medical professional must be on site whenever it is open.

212
Total units
$188K+
Initial investment

Brand Performance Snapshot

Franchised and company-owned unit counts for 2023 through 2025, as reported in the franchisor's FDD.

Unit count by year
Franchised Affiliate
99
2023
156
2024
212
2025
210
Franchised units
2
Affiliate-owned units
212
Total units
+114.1%
3-yr unit growth

Existing Prime IV Hydration & Wellness Franchises for Sale

Operating Prime IV Hydration & Wellness territories listed for sale by their owners or brokers, reviewed before publishing.

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Prime IV Hydration & Wellness Franchise Model Overview

Prime IV centers deliver customized nutrient IV hydration therapy, along with cryotherapy and hormone and peptide therapies, to retail customers in a lounge-style storefront. The setting feels like a day spa, but the business is medically regulated: at least one licensed medical or healthcare professional must be present during all business hours, a medical director is required, and in some states an unlicensed owner may only manage the center under a management agreement with a professional corporation. The investment ranges from low to mid six figures depending mainly on leasehold improvements; an Add-On format lets existing medical practices convert at lower cost. Owners are expected to work in the business full time or install a fully trained manager, and a substantial minimum local marketing spend applies each month. The system has grown quickly, more than doubling since 2023, and almost all units are franchised. Transfers carry a fee of 30% of the then-current franchise fee.

Ideal owner profile

Owner-operator or owner with a fully trained full-time manager running the center
Comfortable with medical regulation, licensed clinical staff and state-specific ownership structures
Healthcare, med-spa or wellness background helpful; licensed professionals can use the Add-On route
Retail sales and local marketing skills to fill appointment books and memberships
Low-to-mid six-figure capital plus a sizable required monthly local marketing budget

Investment Snapshot

Initial franchise fee $49,000 (1st unit; $39,000 each additional bought at the same time)
Total initial investment $187,701 – $606,693
Royalty 7% of Gross Revenues (monthly)
Ad / brand fund 1% of Gross Revenues (may rise to 2%); local advertising minimum of the greater of $2,500/month or 5% of Gross Revenues
FDD year 2026 (unit data through 2025)
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Important disclosure

Brand information on this page — including unit counts, fees, and investment ranges — was compiled by Verified Franchise Resales from the brand's most recent Franchise Disclosure Document and has not been independently verified. Verified Franchise Resales is an independent marketplace and is not affiliated with, endorsed by, or sponsored by Prime IV Hydration & Wellness. Prospective buyers should obtain and review the current FDD, consult qualified legal and financial advisors, and confirm all terms before responding. This page is for informational purposes only and is not an offer to sell or a solicitation to buy a franchise; offers are made only through the FDD in applicable jurisdictions. Read VFR’s Terms of Use before responding to any franchise.